Description

(9H-Fluoren-9-Yl)Methyl 3-Hydroxypyrrolidine-1-Carboxylate is a high-purity, specialized organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its bifunctional structure, incorporating both a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a hydroxypyrrolidine moiety, making it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals. Its precise synthesis and reliable quality are critical for ensuring the success of downstream applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and metabolic disorders.
• Peptide Synthesis: Serves as a protected amino acid derivative or a scaffold modifier in solid-phase and solution-phase peptide synthesis.
• Protecting Group Chemistry: Utilized for the selective protection of amine and alcohol functional groups in multi-step organic syntheses.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the creation of novel polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl 3-Hydroxypyrrolidine-1-Carboxylate
CAS No.	948551-28-8
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Fmoc-3-Hydroxypyrrolidine; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-hydroxypyrrolidine; 3-Hydroxy-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine; 3-Hydroxypyrrolidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester; 1-Fmoc-3-hydroxypyrrolidine; 1-[(9-Fluorenylmethoxy)carbonyl]-3-hydroxypyrrolidine; N-Fmoc-3-hydroxypyrrolidine; 3-Hydroxy-N-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 3-Hydroxypyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring a reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.