Description

Methyl 2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetate is a high-value brominated pyridine derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the substituted pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific bromo- and methoxy-functionalized intermediates.

Basic Information

Product Name	Methyl 2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetate
CAS No.	947688-88-2
Molecular Formula	C9H10BrNO3
Molecular Weight	260.09 g/mol
Synonyms	Methyl (5-bromo-3-methoxypyridin-2-yl)acetate; 2-(5-Bromo-3-methoxy-2-pyridinyl)acetic acid methyl ester; Acetic acid, 2-(5-bromo-3-methoxy-2-pyridinyl)-, methyl ester; 5-Bromo-3-methoxypyridine-2-acetic acid methyl ester; Methyl 5-bromo-3-methoxypicolinate (common misnomer); 947688-88-2; Methyl 2-(5-bromo-3-methoxypyridin-2-yl)ethanoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.