Description

2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetonitrile is a high-purity, versatile pyridine-based nitrile building block essential for advanced organic synthesis. Its molecular structure, featuring both bromo and methoxy substituents, makes it a critical intermediate for constructing complex heterocyclic frameworks. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a precursor for functionalized ligands and monomers used in specialty polymers and advanced materials.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new chemical spaces.

Basic Information

Product Name	2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetonitrile
CAS No.	947688-87-1
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	(5-Bromo-3-methoxy-2-pyridinyl)acetonitrile; 2-(5-Bromo-3-methoxypyridin-2-yl)ethanenitrile; Acetonitrile, 2-(5-bromo-3-methoxy-2-pyridinyl)-; 5-Bromo-3-methoxypicolinonitrile (incorrect but common); 2-Cyanoethyl-5-bromo-3-methoxypyridine; 947688-87-1; 5-Bromo-3-methoxy-2-pyridineacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-3-Methoxypyridin-2-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.