Description

1,3,2-Dioxaborolane, 2-[5-Chloro-2-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, a critical step in constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-chloro substitution patterns.
• Material Science Research: Serves as a functional monomer or building block for creating organic electronic materials, such as polymers for OLEDs or conductive films.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugation reagents due to its reactive boronate group and protected phenol.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis campaigns, given appropriate quality and consistency.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[5-Chloro-2-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	947683-03-6
Molecular Formula	C14H20BClO4
Molecular Weight	298.57 g/mol
Synonyms	5-Chloro-2-(methoxymethoxy)phenylboronic acid pinacol ester; (5-Chloro-2-(methoxymethoxy)phenyl)boronic acid pinacol ester; 2-(5-Chloro-2-(MOM)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; MOM-Protected 5-Chlorophenylboronic Acid Pinacol Ester; [5-Chloro-2-(methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 947683-03-6; Boronic acid, B-[5-chloro-2-(methoxymethoxy)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[5-Chloro-2-(Methoxymethoxy)Phenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines as required for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity. Keep container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area Percent)
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.