Description

1-Oxa-5-Thia-Spiro[5.5]Undecan-9-One CAS NO 947534-48-7 is a high-purity, specialized spirocyclic heterocyclic compound containing both oxygen and sulfur atoms within its unique bridged ring structure. This molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and key synthon for complex organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and other therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity and environmental profile.
• Material Science Research: Acts as a precursor or monomer for developing specialized polymers, ligands for catalysis, or components for organic electronic materials due to its rigid, three-dimensional structure.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, enzyme inhibitors, or bioconjugation reagents.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including research into new cyclization reactions and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-Oxa-5-Thia-Spiro[5.5]Undecan-9-One
CAS No.	947534-48-7
Molecular Formula	C9H14O2S
Molecular Weight	186.27 g/mol
Synonyms	1-Oxa-5-thiaspiro[5.5]undecan-9-one; 9-Oxo-1-oxa-5-thiaspiro[5.5]undecane; 1-Oxa-5-thia-spiro[5.5]undecan-9-one; Spiro[1,3-oxathiane-2,1'-cyclohexan]-4-one (related structural naming); Oxathiaspirodecane derivative
EINECS	Contact for details

Quality Control

Every batch of 1-Oxa-5-Thia-Spiro[5.5]Undecan-9-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with each shipment, detailing specifications such as assay (typically by HPLC or GC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.