Description

5-Bromo-2-Cyclobutylmethoxy-3-Nitro-Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromo, nitro, and cyclobutylmethoxy substituents on a pyridine core, makes it a versatile intermediate for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated nitro-heterocyclic structure.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactive bromo and nitro groups.
• Academic & R&D: A valuable reagent for methodological studies and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	5-Bromo-2-Cyclobutylmethoxy-3-Nitro-Pyridine
CAS No.	947534-28-3
Molecular Formula	C10H11BrN2O3
Molecular Weight	287.11 g/mol
Synonyms	5-Bromo-2-(cyclobutylmethoxy)-3-nitropyridine; 3-Nitro-5-bromo-2-cyclobutylmethoxypyridine; 2-(Cyclobutylmethoxy)-3-nitro-5-bromopyridine; Pyridine, 5-bromo-2-(cyclobutylmethoxy)-3-nitro-; 947534-28-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Cyclobutylmethoxy-3-Nitro-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.