Description

1,4-Dioxa-8-Aza-Spiro[4.6]Undecane, Hydrochloride is a specialized spirocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which is highly valuable for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its spirocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and liquid crystals with specific properties.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes to study biological pathways and enzyme functions.
• Academic & Institutional Research: A valuable reagent for methodology development and exploring new chemical spaces in university and institutional laboratories.

Basic Information

Item	Detail
Product Name	1,4-Dioxa-8-Aza-Spiro[4.6]Undecane, Hydrochloride
CAS No.	947534-11-4
Molecular Formula	C8H15NO2 • HCl
Molecular Weight	193.67 g/mol (Free base: 157.21 g/mol)
Synonyms	8-Aza-1,4-dioxaspiro[4.6]undecane hydrochloride; 1,4-Dioxa-8-azaspiro[4.6]undecane HCl; Spiro[1,3-dioxolane-2,1'-piperidine] hydrochloride; 1-Oxa-4,8-diazaspiro[4.6]undecane hydrochloride (tautomer); 8-Aza-1,4-dioxaspiro[4.6]undecane HCl salt; 1,4-Dioxa-8-azaspiro[4.6]undecane monohydrochloride; 1,4-Dioxa-8-azaspiro[4.6]undecane, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-8-Aza-Spiro[4.6]Undecane, Hydrochloride is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.