Description

Dithia-2-Aza-Spiro[3.4]Octane, Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block with the CAS number 947534-02-3. This spirocyclic compound is valued for its unique heterocyclic structure, which is critical for modulating the physicochemical and biological properties of active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel therapeutic agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic scaffold can contribute to unique modes of action and improved environmental profiles.
• Chemical Biology Probe: Serves as a versatile scaffold for creating molecular probes to study biological pathways and enzyme functions in academic and industrial research settings.
• Material Science Precursor: Potential use as a monomer or precursor in the synthesis of specialized polymers and advanced materials with specific electronic or structural properties.
• Process Chemistry & Scale-Up: Employed in process research and development (PR&D) for optimizing synthetic routes to complex molecules before commercial manufacturing.

Basic Information

Product Name	Dithia-2-Aza-Spiro[3.4]Octane, Hydrochloride
CAS No.	947534-02-3
Molecular Formula	C6H12ClNS2 (Base: C6H11NS2)
Molecular Weight	197.75 g/mol (Base: 161.29 g/mol)
Synonyms	1-Thia-4-azaspiro[4.4]nonane, 1,1-dioxide, hydrochloride; Dithia-2-azaspiro[3.4]octane HCl; 2-Aza-1,4-dithiaspiro[3.4]octane hydrochloride; Spiro[dithia-2-azacyclopentane-3,1'-cyclopentane] hydrochloride; 947534-02-3; Dithiaaza Spirooctane HCl; Advanced Spirocyclic Building Block
EINECS	Contact for details

Quality Control

Our Dithia-2-Aza-Spiro[3.4]Octane, Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.