Description

5-Oxa-8-Thia-2-Aza-Spiro[3.4]Octane, Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compounds in structure-activity relationship (SAR) studies.
• API Development: Serves as a building block in the process development and scale-up of new active pharmaceutical ingredients.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides with complex heterocyclic structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Production: Integrated into multi-step syntheses of specialty chemicals requiring its specific spiro-oxathiazine motif.

Basic Information

Product Name	5-Oxa-8-Thia-2-Aza-Spiro[3.4]Octane, Hydrochloride
CAS No.	947534-00-1
Molecular Formula	C5H8ClNOS
Molecular Weight	165.64 g/mol
Synonyms	5-Oxa-8-thia-2-azaspiro[3.4]octane hydrochloride; 8-Thia-2-aza-5-oxaspiro[3.4]octane hydrochloride; 2-Aza-5-oxa-8-thiaspiro[3.4]octane hydrochloride; Spiro[3.4]octane, 5-oxa-8-thia-2-aza-, hydrochloride; 1-Thia-4,7-diazaspiro[3.4]octane 1-oxide hydrochloride (tautomeric form); 5-Oxa-8-thia-2-aza-spiro[3.4]octane HCl; CAS 947534-00-1
EINECS	Contact for details

Quality Control

Our 5-Oxa-8-Thia-2-Aza-Spiro[3.4]Octane, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.