Description

1-tert-Butoxycarbonyl-1H-Pyrazole-4-Boronic Acid is a high-purity, protected boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs.
• Chemical Biology Probes: Utilized in the construction of molecular probes and bioconjugates for target identification and validation.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Detail
Product Name	1-tert-Butoxycarbonyl-1H-Pyrazole-4-Boronic Acid
CAS No.	947533-31-5
Molecular Formula	C9H15BN2O4
Molecular Weight	226.04 g/mol
Synonyms	1-Boc-1H-Pyrazole-4-Boronic Acid; 1-(tert-Butoxycarbonyl)-1H-pyrazole-4-boronic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid tert-butyl ester; 1H-Pyrazole-1-carboxylic acid, 4-borono-, 1,1-dimethylethyl ester; Boc-Pyrazole-4-Boronic Acid; tert-Butyl 4-boronopyrazole-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 1-tert-Butoxycarbonyl-1H-Pyrazole-4-Boronic Acid is manufactured under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.