Description

2-Acetamidopyridine-5-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a protected amine, makes it an essential intermediate for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its boronic acid functionality for creating diverse chemical scaffolds.
• Material Science Research: Serves as a building block for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for studying biological processes and diagnostics.
• Catalyst Ligand Development: The pyridine and boronic acid motifs can be utilized to develop novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Acetamidopyridine-5-Boronic Acid
CAS No.	947533-21-3
Molecular Formula	C7H9BN2O3
Molecular Weight	179.97 g/mol
Synonyms	5-Borono-2-acetamidopyridine; 2-Acetamido-5-pyridineboronic Acid; N-(5-Boronopyridin-2-yl)acetamide; 2-Pyridineacetamide, 5-borono-; 2-Acetamidopyridine-5-boronic acid pinacol ester (common derivative); 5-(Acetylamino)-2-pyridineboronic acid; 2-Acetylamino-5-pyridylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Acetamidopyridine-5-Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Ensure the storage area is well-ventilated and separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.