Description

4-([2-(Hydroxymethyl)Phenyl]Dimethylsilyl)Benzeneboronic Acid Pinacol Ester, 95% is a high-purity, organosilicon-protected boronic ester derivative. This compound is a critical advanced synthetic intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for creating biaryl and heterobiaryl structures in drug discovery and development.
• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules for therapeutic applications.
• Agrochemical Synthesis: Production of advanced crop protection agents and herbicides requiring specific silicon-containing motifs.
• Materials Science Precursor: Development of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology Probes: Used in the synthesis of probes for studying biological processes and enzyme activity.
• Organic Synthesis: Versatile intermediate for constructing molecules with combined aryl, hydroxymethyl, and silyl functionalities.

Basic Information

Product Name	4-([2-(Hydroxymethyl)Phenyl]Dimethylsilyl)Benzeneboronic Acid Pinacol Ester, 95%
CAS No.	947515-75-5
Molecular Formula	C21H29BO3Si
Molecular Weight	368.36 g/mol
Synonyms	[2-(Dimethyl(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)silyl)phenyl]methanol; 4-(Dimethyl(2-(hydroxymethyl)phenyl)silyl)benzeneboronic Acid Pinacol Ester; (4-(Dimethyl(2-(hydroxymethyl)phenyl)silyl)phenyl)boronic Acid Pinacol Ester; Boronic Acid, B-[4-[dimethyl[2-(hydroxymethyl)phenyl]silyl]phenyl]-, 1,1-dimethylethyl Ester; Pinacol 4-(Dimethyl(2-(hydroxymethyl)phenyl)silyl)benzeneboronate; 4-(Dimethyl(o-hydroxymethylphenyl)silyl)phenylboronic Acid Pinacol Ester; Protected Boronic Ester Intermediate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 95% grade of this advanced intermediate is produced under strict quality protocols to ensure batch-to-batch consistency for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.