Description

1H-Pyrrolo[2,3-B]Pyridin-3-Ol, 1-(Phenylsulfonyl)-, 3-Formate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of targeted therapies for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel chemical libraries.
• Biochemical Research: Employed as a reference standard or a probe molecule in enzymatic assays and target validation studies.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and process development for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug discovery.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridin-3-Ol, 1-(Phenylsulfonyl)-, 3-Formate
CAS No.	947498-93-3
Molecular Formula	C14H10N2O4S
Molecular Weight	302.31 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl formate; 1H-Pyrrolo[2,3-b]pyridin-3-ol, 1-(phenylsulfonyl)-, 3-formate; 1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-3-yl formate; 947498-93-3; 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-ol formate; 1-Phenylsulfonyl-1H-pyrrolo[2,3-b]pyridin-3-yl formate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-3-Ol, 1-(Phenylsulfonyl)-, 3-Formate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.