Description

tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrrolopyridine-piperidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted small-molecule therapeutics. It is primarily needed by R&D and process development teams in the pharmaceutical and biotechnology industries for the development of novel kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation & Probe Synthesis: Utilized for creating chemical probes and tagged molecules for biological assay development.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery and development pipelines.

Basic Information

Product Name	tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate
CAS No.	947498-92-2
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(7-azaindol-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine; 4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1-piperidinecarboxylate; 3-(1-Boc-4-piperidyl)-7-azaindole; 947498-92-2; BOC-4-(7-Azaindol-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.