Description

4-Bromopyridin-2(1H)-One is a versatile brominated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its reactivity as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), advanced materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and photoactive materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and other complex structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.
• Fine Chemical Production: Integral to the custom synthesis of specialty chemicals for various high-tech industries.

Basic Information

Product Name	4-Bromopyridin-2(1H)-One
CAS No.	947407-84-3
Molecular Formula	C5H4BrNO
Molecular Weight	173.99 g/mol
Synonyms	4-Bromo-2-hydroxypyridine; 4-Bromo-2-pyridone; 4-Bromo-2(1H)-pyridinone; 2-Hydroxy-4-bromopyridine; 4-Bromo-1H-pyridin-2-one; 4-Bromopyridin-2-ol; 4-Bromo-2-pyridinol
EINECS	Contact for details

Quality Control

Our 4-Bromopyridin-2(1H)-One is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.