Description

4-Amino-5,6-Dihydro-2H-Pyridine-1,3-Dicarboxylicacid1-tert-Butylester3-Ethylester is a high-purity, protected amino-dihydropyridine dicarboxylate derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles, which are central to numerous active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Chemical Research & Development: Serves as a versatile precursor for creating complex molecular libraries in medicinal chemistry and for exploring new synthetic methodologies.
• Ligand and Catalyst Development: The amino and ester functional groups make it a candidate for developing novel ligands for metal catalysis or organocatalysts.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or functionalized materials requiring specific nitrogen-based heterocycles.

Basic Information

Product Name	4-Amino-5,6-Dihydro-2H-Pyridine-1,3-Dicarboxylicacid1-tert-Butylester3-Ethylester
CAS No.	947403-75-0
Molecular Formula	C13H22N2O4
Molecular Weight	270.33 g/mol
Synonyms	1-tert-Butyl 3-ethyl 4-amino-5,6-dihydro-2H-pyridine-1,3-dicarboxylate; 4-Amino-1,3-diethyl 5,6-dihydro-2H-pyridine-1,3-dicarboxylate (tert-butyl/ethyl ester); 4-Amino-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester; Ethyl 4-amino-1-(tert-butoxycarbonyl)-5,6-dihydro-2H-pyridine-3-carboxylate; 4-Amino-N-Boc-5,6-dihydropyridine-3-carboxylic acid ethyl ester; 947403-75-0; Amino-dihydropyridine dicarboxylate derivative
EINECS	Contact for details

Quality Control

Our 4-Amino-5,6-Dihydro-2H-Pyridine-1,3-Dicarboxylicacid1-tert-Butylester3-Ethylester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.