Description

6-Aminopyrazine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the pyrazine ring and various aryl or vinyl halides.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing aminopyrazine motifs for kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel bidentate or tridentate ligands for transition metal catalysis.
• Materials Science & OLED Development: A precursor for electron-transport materials and emissive layers in organic light-emitting diodes (OLEDs) and other electronic devices.
• Chemical Biology & Probe Development: Useful for creating molecular probes and bioconjugates due to the reactivity of the boronic ester and the functionalizable amine group.

Basic Information

Product Name	6-Aminopyrazine-2-Boronic Acid Pinacol Ester
CAS No.	947249-41-4
Molecular Formula	C11H16BN3O2
Molecular Weight	233.08 g/mol
Synonyms	6-Amino-2-pyrazinylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-5-amine; 5-Amino-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine; 6-Aminopyrazine-2-boronic acid pinacol ester; 2-Pyrazinylboronic acid, 6-amino-, 1,3,2-dioxaborolane deriv.; (6-Aminopyrazin-2-yl)boronic acid pinacol ester; 6-Amino-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine
EINECS	Contact for details

Quality Control

Our 6-Aminopyrazine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.