Description

2-Bromo-3-(Difluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and difluoromethoxy substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluoromethoxy and bromopyridine motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel pyridine-based ligands for catalytic systems.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological mechanisms and diagnostics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-3-(Difluoromethoxy)Pyridine
CAS No.	947249-27-6
Molecular Formula	C6H4BrF2NO
Molecular Weight	224.00 g/mol
Synonyms	3-(Difluoromethoxy)-2-bromopyridine; 2-Bromo-3-difluoromethoxypyridine; Pyridine, 2-bromo-3-(difluoromethoxy)-; 947249-27-6; 2-Bromo-3-(difluoromethoxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-(Difluoromethoxy)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment to guarantee consistency and reliability for your critical syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.