Description

Acetamide, N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl]- is a high-value, functionalized heterocyclic building block containing a protected boronic ester group. This compound is critical for modern synthetic chemistry, enabling the precise construction of complex molecular architectures through cross-coupling reactions. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used to create novel active ingredients with specific biological activity for crop protection products.
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biological target identification and study.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.
• Ligand and Catalyst Development: Used to synthesize novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Acetamide, N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl]-
CAS No.	947249-08-3
Molecular Formula	C16H22BN3O3
Molecular Weight	315.18 g/mol
Synonyms	N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide; 2-Acetamido-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-amine, N-acetyl-; Acetamide, N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-imidazo[1,2-a]pyridin-2-yl]-; 947249-08-3; Imidazo[1,2-a]pyridine-2-acetamide boronic ester derivative
EINECS	Contact for details

Quality Control

Our Acetamide, N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.