Description

2-Pyridinecarboxamide, 6-Methyl-n-(1-Methyl-1H-Pyrazol-3-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex heterocyclic scaffolds. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: A versatile boronate ester reagent for forming carbon-carbon bonds under mild conditions, crucial for constructing complex organic molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for studying biological pathways and diagnostics.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Pyridinecarboxamide, 6-Methyl-n-(1-Methyl-1H-Pyrazol-3-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	947179-32-0
Molecular Formula	C17H23BN4O3
Molecular Weight	342.21 g/mol
Synonyms	6-Methyl-N-(1-methyl-1H-pyrazol-3-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-N-(1-methyl-1H-pyrazol-3-yl)pyridine-2-carboxamide; 2-Pyridinecarboxamide, 6-methyl-N-(1-methyl-1H-pyrazol-3-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[6-[[(1-methyl-1H-pyrazol-3-yl)amino]carbonyl]-2-methyl-4-pyridinyl]-, 1,1-dimethylethyl ester; 947179-32-0; 6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(1-methyl-1H-pyrazol-3-yl)picolinamide
EINECS	Contact for details

Quality Control

Our 947179-32-0 is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.