Description

2-Pyridinecarboxamide, 6-Methyl-n-(2-Methyl-4-Pyridinyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional boronic ester derivative, serving as a critical advanced pharmaceutical intermediate in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex biaryl and heterobiaryl scaffolds. This compound is essential for research and development teams in the pharmaceutical, agrochemical, and material science industries who require precise and reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl groups under mild conditions, crucial for creating complex molecular architectures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science & OLED Development: Serves as a precursor for organic electronic materials, including light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A vital reagent for synthetic methodology development and medicinal chemistry programs in academic and CRO laboratories.

Basic Information

Product Name	2-Pyridinecarboxamide, 6-Methyl-n-(2-Methyl-4-Pyridinyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	947179-30-8
Molecular Formula	C19H24BN3O3
Molecular Weight	353.22 g/mol
Synonyms	6-Methyl-N-(2-methylpyridin-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-N-(2-methylpyridin-4-yl)picolinamide; 947179-30-8; Boronic acid, B-[6-[[(2-methyl-4-pyridinyl)amino]carbonyl]-2-methyl-3-pyridinyl]-, 1,3-propanediol cyclic ester; 6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-methylpyridin-4-yl)picolinamide
EINECS	Contact for details

Quality Control

Every batch of our 2-Pyridinecarboxamide derivative is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and pharmaceutical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC/NMR), identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.