Description

2-Pyridinecarboxamide, 6-Methyl-n-(4-Methyl-2-Thiazolyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Research: Used to create novel fungicides, herbicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Precursor for the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for target identification and validation studies.
• Catalyst Ligand Synthesis: Serves as a precursor for novel ligand systems in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific boronate functionalization.

Basic Information

Item	Detail
Product Name	2-Pyridinecarboxamide, 6-Methyl-n-(4-Methyl-2-Thiazolyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	947179-28-4
Molecular Formula	C17H24BN3O3S
Molecular Weight	361.26 g/mol
Synonyms	6-Methyl-N-(4-methylthiazol-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-N-(4-methyl-1,3-thiazol-2-yl)pyridine-2-carboxamide; 947179-28-4; 2-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[6-[[(4-methyl-2-thiazolyl)amino]carbonyl]-2-pyridinyl]-, 1,3-propanediol cyclic ester
EINECS	Contact for details

Quality Control

Every batch of our 2-Pyridinecarboxamide derivative is produced under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and structural integrity suitable for demanding R&D and scale-up applications. A detailed Certificate of Analysis (COA) providing HPLC purity, NMR confirmation, and residual solvent data is supplied with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.