Description

4-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridin-3-Amine is a high-value halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridin-3-Amine
CAS No.	947146-74-9
Molecular Formula	C6H3BrClF3N2
Molecular Weight	275.45 g/mol
Synonyms	3-Amino-4-bromo-2-chloro-6-(trifluoromethyl)pyridine; 4-Bromo-2-chloro-6-(trifluoromethyl)-3-pyridinamine; 4-Bromo-2-chloro-6-(trifluoromethyl)pyridin-3-ylamine; 947146-74-9; 4-Bromo-2-chloro-6-trifluoromethyl-pyridin-3-ylamine; 4-Bromo-2-chloro-6-(trifluoromethyl)-3-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Chloro-6-(Trifluoromethyl)Pyridin-3-Amine is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.