Description

2(1H)-Pyridinone, 4-Hydroxy-6-(Trifluoromethyl)- is a high-value trifluoromethylated pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a pyridinone core with a hydroxy and a trifluoromethyl group, makes it indispensable for creating novel compounds with enhanced properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, anti-inflammatory, or anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Employed as a precursor for developing specialty chemicals, ligands for catalysis, or functional monomers for advanced polymers.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, enzyme inhibitors, and other tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2(1H)-Pyridinone, 4-Hydroxy-6-(Trifluoromethyl)-
CAS No.	947144-32-3
Molecular Formula	C6H4F3NO2
Molecular Weight	179.10 g/mol
Synonyms	4-Hydroxy-6-(trifluoromethyl)pyridin-2(1H)-one; 6-(Trifluoromethyl)-4-hydroxypyridin-2(1H)-one; 4-Hydroxy-6-(trifluoromethyl)-1H-pyridin-2-one; 4-Hydroxy-6-trifluoromethyl-2(1H)-pyridinone; 4-Hydroxy-6-trifluoromethyl-2-pyridone; 6-Trifluoromethyl-4-hydroxy-2-pyridone; 4-Hydroxy-6-(trifluoromethyl)-2-pyridone
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyridinone, 4-Hydroxy-6-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.