Description

1'H-Spiro[Piperidine-3,2'-Quinazolin]-4'(3'H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic quinazolinone class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology targets. The precise molecular architecture of this spiro-fused scaffold offers unique three-dimensional properties valuable for probing biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery Programs: Employed in the synthesis of potential therapeutic agents targeting neurological disorders, such as anxiety, depression, or neurodegenerative diseases.
• Oncology Research: Utilized as a building block for developing novel small-molecule inhibitors for cancer therapy.
• Chemical Biology Probes: Acts as a specialized tool compound for investigating specific enzyme functions or protein interactions in biological systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1'H-Spiro[Piperidine-3,2'-Quinazolin]-4'(3'H)-One
CAS No.	947017-23-4
Molecular Formula	C12H13N3O
Molecular Weight	215.25 g/mol
Synonyms	Spiro[piperidine-3,2'-quinazolin]-4'(3'H)-one; 1'H-Spiro(piperidine-3,2'-quinazolin)-4'(3'H)-one; 4'(3'H)-Quinazolinone, 1'H-spiro[piperidine-3,2'-]; Spiro[piperidine-3,2'-quinazolin]-4'-one; 1'H-Spiro[piperidine-3,2'-quinazolin]-4'(3'H)-one; 947017-23-4; Spirocyclic quinazolinone piperidine derivative
EINECS	Contact for details

Quality Control

Our 1'H-Spiro[Piperidine-3,2'-Quinazolin]-4'(3'H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.