Description

1-[(Fmoc-Amino)Methyl]Cyclopentanecarboxylic Acid is a specialized, high-purity building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, high-quality intermediates for complex molecular construction. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and peptide-based products.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative, it serves as a key intermediate for introducing constrained, cyclopentane-based structures into peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptidomimetics and active pharmaceutical ingredients (APIs) where a rigid, cyclopentane scaffold is required to influence bioactivity and metabolic stability.
• Combinatorial Chemistry Libraries: A valuable building block for creating diverse compound libraries for high-throughput screening in drug discovery programs.
• Bioconjugation and Probe Development: Employed in the synthesis of labeled peptides and molecular probes for diagnostic and biochemical research applications.
• Custom Peptide Service Providers: Essential raw material for CROs and CDMOs offering bespoke peptide synthesis services to the biopharma industry.

Basic Information

Product Name	1-[(Fmoc-Amino)Methyl]Cyclopentanecarboxylic Acid
CAS No.	946727-65-7
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	Fmoc-Amc-OH; 1-[(9-Fluorenylmethoxycarbonylamino)methyl]cyclopentanecarboxylic Acid; 1-[(Fmoc-Amino)methyl]cyclopentane-1-carboxylic Acid; 1-(Fmoc-aminomethyl)cyclopentanecarboxylic acid; N-[(1-Carboxycyclopentyl)methyl]-9H-fluoren-9-ylmethoxycarboxamide; 1-(Fmoc-aminomethyl)cyclopentane-1-carboxylic acid; (1-(((9H-Fluoren-9-yl)methoxy)carbonylamino)methyl)cyclopentane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(Fmoc-Amino)Methyl]Cyclopentanecarboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.