Description

(2S)-2,4-Dihydroxy-3,3-Dimethylbutanoic Acid CAS NO 1112-32-9 is a chiral, multifunctional organic acid characterized by its two hydroxyl groups and a carboxylic acid moiety on a branched carbon skeleton. This compound serves as a valuable building block and chiral intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical industries. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), vitamins, and specialty chemicals where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of statin drugs, antibiotics, and other therapeutic agents.
• Vitamin Synthesis: Building block for the production of vitamins and coenzymes, such as pantothenic acid (Vitamin B5) derivatives.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Serves as a substrate or intermediate in enzymatic studies and metabolic pathway research.
• Ligand and Catalyst Development: Utilized for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Cosmetic Ingredients: Potential intermediate for synthesizing moisturizing or skin-conditioning agents.

Basic Information

Product Name	(2S)-2,4-Dihydroxy-3,3-Dimethylbutanoic Acid
CAS No.	1112-32-9
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	(S)-2,4-Dihydroxy-3,3-dimethylbutyric acid; (2S)-2,4-Dihydroxy-3,3-dimethylbutanoic acid; D-2,4-Dihydroxy-3,3-dimethylbutyric acid; (S)-Pantolactone acid; (S)-3,3-Dimethyl-2,4-dihydroxybutyric acid; (S)-3-Hydroxy-4,4-dimethyl-dihydrofuran-2(3H)-one (tautomer); (S)-Pantoyl lactone acid
EINECS	214-195-6

Quality Control

Our (2S)-2,4-Dihydroxy-3,3-Dimethylbutanoic Acid is produced under a strict quality management system. Each batch is analyzed to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) are provided with each shipment, detailing specifications for assay, enantiomeric excess, and impurity profiles. We support compliance with cGMP, ICH guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.