Description

(R)-2-Hydroxymethylpropanoic Acid is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its ability to impart stereochemical control in the production of complex molecules, ensuring high enantiomeric purity in the final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral precursors for API development and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in transition metal catalysis and enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a specific enantiomeric form.
• Polymer Modification: Can be used to introduce chiral centers into polymer backbones for advanced materials with specific optical or mechanical properties.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and for studying stereoselective reaction mechanisms.

Basic Information

Product Name	(R)-2-Hydroxymethylpropanoic Acid
CAS No.	1910-47-0
Molecular Formula	C4H8O3
Molecular Weight	104.10 g/mol
Synonyms	(R)-2-(Hydroxymethyl)propanoic Acid; (R)-2-Methyl-3-hydroxypropionic Acid; D-2-Hydroxymethylpropionic Acid; (R)-3-Hydroxy-2-methylpropanoic Acid; (R)-2-Methyl-3-hydroxypropanoic Acid; (R)-β-Hydroxymethylpropionic Acid; (2R)-2-(Hydroxymethyl)propanoic Acid
EINECS	217-618-6

Quality Control

Our (R)-2-Hydroxymethylpropanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, assay, chiral purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.