Description

(S)-2,3,3-Trimethylbutanoic Acid is a high-purity chiral carboxylic acid characterized by its branched alkyl chain and specific stereochemistry. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, offering precise structural control for complex molecule construction. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can be critical for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Industry: Potential intermediate for creating specific, high-value aroma chemicals with unique olfactory properties.
• Advanced Material Research: Employed in the development of specialty polymers and liquid crystals where the bulky, chiral side chain influences material properties.
• Academic and Process Chemistry: A valuable reagent for methodological development in stereoselective synthesis and scale-up process optimization.

Basic Information

Product Name	(S)-2,3,3-Trimethylbutanoic Acid
CAS No.	13332-31-5
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(S)-2,3,3-Trimethylbutyric Acid; (S)-TMBA; (S)-2,3,3-Trimethyl-1-butanoic Acid; (S)-2,3,3-Trimethylbutanoic Acid; L-2,3,3-Trimethylbutanoic Acid; (2S)-2,3,3-Trimethylbutanoic Acid; (S)-α,β,β-Trimethylbutyric Acid
EINECS	Contact for details

Quality Control

Our (S)-2,3,3-Trimethylbutanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), specific rotation, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is a strong acid/organic solvent; handle with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.