Description

3-(4-Chloro-2-Fluorophenoxy)Pyrrolidine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 946727-20-4. This compound is a critical building block in modern synthetic organic chemistry, valued for its unique pyrrolidine-phenoxy structure which enables the synthesis of complex, bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated phenoxy moiety.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Employed in the creation of specialized ligands for asymmetric catalysis and metal complexation.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored properties.

Basic Information

Product Name	3-(4-Chloro-2-Fluorophenoxy)Pyrrolidine
CAS No.	946727-20-4
Molecular Formula	C10H11ClFNO
Molecular Weight	215.65 g/mol
Synonyms	3-[(4-Chloro-2-fluorophenyl)oxy]pyrrolidine; Pyrrolidine, 3-[(4-chloro-2-fluorophenoxy)]-; 946727-20-4; 3-(4-Chloro-2-fluoro-phenoxy)-pyrrolidine; 3-(4-Chloro-2-fluorophenoxy)pyrrolidine hydrochloride (if applicable, salt form); 4-Chloro-2-fluoro-3-pyrrolidinyloxybenzene
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chloro-2-Fluorophenoxy)Pyrrolidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent batch-to-batch quality suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.