Description

4-Chloro-6-(Trifluoromethyl)Pyrido[3,2-D]Pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyridopyrimidine scaffold, which serves as a privileged structure for modulating biological activity and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting complex biological pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridopyrimidine core.
• Material Science Precursor: Serves as a building block for creating specialized organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular signaling processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	4-Chloro-6-(Trifluoromethyl)Pyrido[3,2-D]Pyrimidine
CAS No.	946594-93-0
Molecular Formula	C8H3ClF3N3
Molecular Weight	233.58 g/mol
Synonyms	4-Chloro-6-(trifluoromethyl)pyrido[3,2-d]pyrimidine; 4-Chloro-6-(trifluoromethyl)-pyrido[3,2-d]pyrimidine; 4-Chloro-6-trifluoromethylpyrido[3,2-d]pyrimidine; Pyrido[3,2-d]pyrimidine, 4-chloro-6-(trifluoromethyl)-; 946594-93-0; 4-Chloro-6-(trifluoromethyl)pyrido[3,2-d]pyrimidin; 4-Chloro-6-trifluoromethyl-pyrido[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Trifluoromethyl)Pyrido[3,2-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.