Description

(S)-Neopentyl2-Aminopropanoatehydrochloride CAS NO 946511-98-4 is a chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. Its primary value lies in providing a sterically hindered, enantiomerically pure scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), peptide mimetics, and specialized catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel APIs, especially in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetics & Prodrug Design: Used to introduce the (S)-2-aminopropanoate (alanine) moiety with a neopentyl protecting group, enhancing metabolic stability and membrane permeability.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or organocatalysts used in stereoselective transformations.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides and plant growth regulators.
• Academic & R&D: Valuable reference standard and starting material in medicinal chemistry and synthetic methodology research.
• Custom Synthesis: Foundation for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	(S)-Neopentyl2-Aminopropanoatehydrochloride
CAS No.	946511-98-4
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	(S)-2-Aminopropanoic acid neopentyl ester hydrochloride; L-Alanine neopentyl ester hydrochloride; (S)-Neopentyl alaninate hydrochloride; Neopentyl L-alaninate hydrochloride; (S)-1,1-Dimethylpropyl 2-aminopropanoate hydrochloride; 946511-98-4; (S)-2-(tert-Butoxycarbonylamino)propionic acid neopentyl ester hydrochloride (related protected form)
EINECS	Contact for details

Quality Control

Our (S)-Neopentyl2-Aminopropanoatehydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.