Description

3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value boronic ester derivative that serves as a critical synthetic intermediate. Its primary value lies in its role as a versatile building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Building block for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic electronic materials.
• Liquid Crystal & Polymer Chemistry: Intermediate for creating advanced monomers and polymers with specific optical or mechanical properties.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex boronic acid derivatives.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	946427-03-8
Molecular Formula	C₁₃H₁₉BO₃
Molecular Weight	234.10 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylphenol; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 3-Methyl-4-(pinacolatoboron)phenol; Phenol, 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 946427-03-8; Boronic acid, B-[2-hydroxy-5-methylphenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.