Description

1-(Pyrid-3-Ylmethyl)Piperidine-4-Carboxylic Acid Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in the fields of neuroscience and oncology. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for API manufacturing under GMP conditions.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and receptor binding studies.
• Custom Synthesis: Foundation for the custom manufacturing of specialized derivatives and analogs for client-specific research programs.

Basic Information

Product Name	1-(Pyrid-3-Ylmethyl)Piperidine-4-Carboxylic Acid Dihydrochloride
CAS No.	946409-40-1
Molecular Formula	C13H18N2O2 · 2HCl
Molecular Weight	307.21 g/mol (free base: 234.30 g/mol)
Synonyms	1-[(Pyridin-3-yl)methyl]piperidine-4-carboxylic acid dihydrochloride; 3-[(4-Carboxypiperidin-1-yl)methyl]pyridine dihydrochloride; 1-(Pyridin-3-ylmethyl)piperidine-4-carboxylic acid hydrochloride (1:2); Piperidine-4-carboxylic acid, 1-[(3-pyridinyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyrid-3-Ylmethyl)Piperidine-4-Carboxylic Acid Dihydrochloride is manufactured and tested to meet the stringent requirements of pharmaceutical R&D and development-scale synthesis. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to a robust quality management system to ensure batch-to-batch consistency and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.