Description

tert-Butyl 4-{4-[(Methylamino)Methyl]Pyrid-2-Yl}Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a protected amine and a substituted pyridine moiety. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly for targeted therapies.
• API Synthesis: Serves as a key building block for constructing complex molecules with potential activity in oncology and neurological disorders.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRAMOs) for bespoke chemical synthesis projects.
• Process Development: Supports scale-up and process chemistry development for new pharmaceutical manufacturing routes.

Basic Information

Product Name	tert-Butyl 4-{4-[(Methylamino)Methyl]Pyrid-2-Yl}Piperazine-1-Carboxylate
CAS No.	946409-15-0
Molecular Formula	C16H26N4O2
Molecular Weight	306.41 g/mol
Synonyms	1-Boc-4-[4-[(Methylamino)methyl]-2-pyridyl]piperazine; tert-Butyl 4-[4-[(methylamino)methyl]-2-pyridinyl]-1-piperazinecarboxylate; 4-[4-[(Methylamino)methyl]pyridin-2-yl]piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[4-[(methylamino)methyl]-2-pyridyl]piperazine; BOC-protected 4-(4-(methylaminomethyl)pyridin-2-yl)piperazine; 946409-15-0; N-Boc-4-(4-(methylaminomethyl)pyridin-2-yl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-{4-[(Methylamino)Methyl]Pyrid-2-Yl}Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.