Description

4-Bromo-1-Methyl-2-Phenyl-5-[(2,2,2-Trifluoroethoxy)Methyl]-1,2-Dihydro-3H-Pyrazol-3-One is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring bromine and trifluoroethoxy substituents, makes it a critical intermediate for constructing novel compounds with tailored properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors, where it serves as a key precursor for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A versatile scaffold for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bromine and fluorine-containing groups can enhance biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials due to its unique halogenated structure.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, functionalized pyrazolone derivatives.

Basic Information

Product Name	4-Bromo-1-Methyl-2-Phenyl-5-[(2,2,2-Trifluoroethoxy)Methyl]-1,2-Dihydro-3H-Pyrazol-3-One
CAS No.	946386-83-0
Molecular Formula	C14H12BrF3N2O2
Molecular Weight	377.16 g/mol
Synonyms	4-Bromo-1-methyl-2-phenyl-5-[(2,2,2-trifluoroethoxy)methyl]-1H-pyrazol-3(2H)-one; 4-Bromo-1-methyl-2-phenyl-5-(2,2,2-trifluoroethoxymethyl)-2H-pyrazol-3-one; 1,2-Dihydro-3H-pyrazol-3-one, 4-bromo-1-methyl-2-phenyl-5-[(2,2,2-trifluoroethoxy)methyl]-; 946386-83-0; 4-Bromo-1-methyl-2-phenyl-5-(trifluoroethoxymethyl)pyrazol-3-one; 5-[(2,2,2-Trifluoroethoxy)methyl]-4-bromo-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-1-Methyl-2-Phenyl-5-[(2,2,2-Trifluoroethoxy)Methyl]-1,2-Dihydro-3H-Pyrazol-3-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects with custom synthesis and specification tailoring to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.