Description

2-Chloro-6-Thiophen-2-Yl-Nicotinonitrile is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the research of organic semiconductors, conductive polymers, and advanced organic materials.
• Chemical Synthesis Scaffold: Employed in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental research and custom synthesis projects.

Basic Information

Product Name	2-Chloro-6-Thiophen-2-Yl-Nicotinonitrile
CAS No.	946385-78-0
Molecular Formula	C10H5ClN2S
Molecular Weight	220.68 g/mol
Synonyms	2-Chloro-6-(thiophen-2-yl)nicotinonitrile; 2-Chloro-6-(2-thienyl)-3-pyridinecarbonitrile; 3-Cyano-2-chloro-6-(2-thienyl)pyridine; 2-Chloro-6-(thiophen-2-yl)pyridine-3-carbonitrile; 2-Chloro-6-thiophen-2-yl-nicotinonitrile; 946385-78-0; 2-(2-Chloro-3-cyanopyridin-6-yl)thiophene
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Thiophen-2-Yl-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.