Description

4-(3-Cyano-6-Phenyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional chemical building block featuring a piperazine core protected by a tert-butyloxycarbonyl (Boc) group and a substituted pyridine moiety. This compound is critical for medicinal chemistry and pharmaceutical research, serving as a versatile intermediate in the synthesis of complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Scaffold: Used in combinatorial chemistry and high-throughput screening libraries due to its piperazine and heterocyclic structure.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides, leveraging its bioactive pyridine core.
• Chemical Biology Probe Development: Utilized for creating labeled compounds and probes to study biological pathways and protein interactions.
• Material Science Research: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system and coordinating nitrogen atoms.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the custom production of complex, patent-protected molecules for clients.

Basic Information

Product Name	4-(3-Cyano-6-Phenyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	946385-51-9
Molecular Formula	C21H24N4O2
Molecular Weight	364.45 g/mol
Synonyms	tert-Butyl 4-(3-cyano-6-phenylpyridin-2-yl)piperazine-1-carboxylate; 2-Piperazinecarboxylic acid, 4-(3-cyano-6-phenyl-2-pyridinyl)-, 1,1-dimethylethyl ester; 4-(3-Cyano-6-phenylpyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-(3-cyano-6-phenyl-2-pyridyl)piperazine; 946385-51-9; 4-(3-Cyano-6-phenyl-2-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(3-Cyano-6-Phenyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are provided with every shipment. We support compliance with relevant frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept sealed under inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.