Description

2-Chloro-6-Pyrazin-2-Yl-Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules and investigational new chemical entities.
• Kinase Inhibitor Development: Used in research and production of protein kinase inhibitors for targeted cancer therapies.
• Agrochemical Research: Acts as a building block for developing new crop protection agents and pesticides.
• Material Science: Employed in the creation of specialized organic ligands and functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services.

Basic Information

Product Name	2-Chloro-6-Pyrazin-2-Yl-Nicotinonitrile
CAS No.	946385-06-4
Molecular Formula	C10H5ClN4
Molecular Weight	216.63 g/mol
Synonyms	2-Chloro-6-(pyrazin-2-yl)nicotinonitrile; 2-Chloro-6-(2-pyrazinyl)-3-pyridinecarbonitrile; Nicotinonitrile, 2-chloro-6-(2-pyrazinyl)-; 3-Pyridinecarbonitrile, 2-chloro-6-(2-pyrazinyl)-; 946385-06-4; 2-Pyrazinecarbonitrile, 6-chloro-3-(2-pyrazinyl)- (related); 2-Chloro-6-pyrazin-2-ylnicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Pyrazin-2-Yl-Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.