Description

2-(3-Ethynyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane CAS NO 946168-04-3 is a high-purity, advanced boronic ester building block featuring a reactive ethynyl group. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for constructing conjugated organic molecules and electron-transport materials in display and lighting technologies.
• Polymer & Material Science: Enables the synthesis of specialty polymers, dendrimers, and advanced materials with tailored electronic or mechanical properties.
• Ligand & Catalyst Development: Employed to create novel bidentate or polydentate ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and labeling strategies in probe and tool molecule development.

Basic Information

Product Name	2-(3-Ethynyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	946168-04-3
Molecular Formula	C14H17BO2
Molecular Weight	228.10 g/mol
Synonyms	3-Ethynylbenzeneboronic Acid Pinacol Ester; (3-Ethynylphenyl)boronic Acid Pinacol Ester; 3-Ethynylphenylboronic Acid Pinacol Ester; 2-(3-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1,3,2-Dioxaborolane, 2-(3-ethynylphenyl)-4,4,5,5-tetramethyl-; 3-Ethynylphenyl-Bpin; 3-Ethynyl-Phenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-(3-Ethynyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.