Description

2-Chloro-3-Fluoro-4-Pyridinemethanol is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	2-Chloro-3-Fluoro-4-Pyridinemethanol
CAS No.	946127-54-4
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	(2-Chloro-3-fluoropyridin-4-yl)methanol; 4-Pyridinemethanol, 2-chloro-3-fluoro-; 2-Chloro-3-fluoro-4-(hydroxymethyl)pyridine; 3-Fluoro-2-chloro-4-pyridinemethanol; 2-Chloro-3-fluoro-4-hydroxymethylpyridine; 2-Chloro-3-fluoropyridine-4-methanol
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoro-4-Pyridinemethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.