Description

(S)-1-(5-Bromopyridin-2-Yl)Pyrrolidin-3-Ol is a high-value chiral building block and intermediate of significant importance in modern synthetic chemistry. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and advanced materials, where its specific stereochemistry and functional groups enable precise molecular construction. Pharmaceutical researchers and fine chemical manufacturers need it for the synthesis of complex molecules, particularly in the areas of drug discovery and agrochemical development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty chemicals and functional materials requiring a defined molecular architecture.
• Academic and R&D Laboratories: Essential for methodological studies in organic synthesis and medicinal chemistry research at universities and corporate R&D centers.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	(S)-1-(5-Bromopyridin-2-Yl)Pyrrolidin-3-Ol
CAS No.	946002-90-0
Molecular Formula	C9H11BrN2O
Molecular Weight	243.10 g/mol
Synonyms	(3S)-1-(5-Bromo-2-pyridinyl)-3-pyrrolidinol; (S)-1-(5-Bromo-2-pyridyl)pyrrolidin-3-ol; 1-(5-Bromopyridin-2-yl)-L-prolinol; (S)-3-Hydroxy-1-(5-bromopyridin-2-yl)pyrrolidine; 946002-90-0; (S)-1-(5-Bromo-2-pyridinyl)-3-pyrrolidinol; (S)-1-(5-Bromopyridin-2-yl)pyrrolidin-3-ol; 5-Bromo-2-[(3S)-3-hydroxypyrrolidin-1-yl]pyridine
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Bromopyridin-2-Yl)Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.