Description

2-Chloro-3-Methyl-6-(Trifluoromethyl)-Pyridine is a high-value, multi-functional halogenated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and agrochemical building block, prized for its unique trifluoromethyl and chloro substituents which impart desirable biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development teams in the crop protection and pharmaceutical industries for synthesizing novel active ingredients.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in central nervous system (CNS) and anti-infective research programs.
• Material Science Research: Employed as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Negishi cross-coupling reactions to create complex biaryl structures.
• Nucleophilic Aromatic Substitution: The chloro group is reactive towards various nucleophiles, enabling the introduction of diverse functional groups.

Basic Information

Product Name	2-Chloro-3-Methyl-6-(Trifluoromethyl)-Pyridine
CAS No.	945971-02-8
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-3-methyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-chloro-3-methylpyridine; 3-Methyl-2-chloro-6-trifluoromethylpyridine; 2-Chloro-3-methyl-6-trifluoromethylpyridine; Pyridine, 2-chloro-3-methyl-6-(trifluoromethyl)-; 945971-02-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methyl-6-(Trifluoromethyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding GMP-scale pharmaceutical synthesis and advanced agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.