Description

2-(n-Methylaminocarbonyl)-5-Pyridineboronic Acid Pincol Ester is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. This compound is critical for facilitating efficient Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex, functionalized heterocyclic systems. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials. The product, identified by CAS number 945863-21-8, is supplied with stringent quality control to ensure batch-to-batch consistency and optimal reaction performance.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Synthesis: Enables the construction of complex, substituted pyridine derivatives via palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the preparation of novel bidentate ligands for catalytic systems.
• Academic and R&D: A valuable reagent for medicinal chemistry and synthetic methodology research in university and corporate laboratories.

Basic Information

Item	Details
Product Name	2-(n-Methylaminocarbonyl)-5-Pyridineboronic Acid Pincol Ester
CAS No.	945863-21-8
Molecular Formula	C13H19BN2O3
Molecular Weight	262.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methylpicolinamide; 2-(Methylcarbamoyl)pyridine-5-boronic acid pinacol ester; N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 5-Borono-N-methylpyridine-2-carboxamide pinacol ester; 2-Carbamoyl-5-pyridineboronic acid pinacol ester, N-methyl-; (5-(Methylcarbamoyl)pyridin-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-(n-Methylaminocarbonyl)-5-Pyridineboronic Acid Pincol Ester is manufactured and tested under a strict quality management system. We guarantee high chemical purity and identity confirmed by advanced analytical techniques, including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.