Description

(E)-Ethyl 2-Oxo-4-(1H-Pyrrol-2-Yl)But-3-Enoate CAS NO 945736-25-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique α,β-unsaturated ester structure fused with a pyrrole moiety. This compound is of significant commercial interest for its role as a versatile building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides due to its bioactive heterocyclic scaffold.
• Organic Synthesis Building Block: Serves as a crucial reactant for constructing complex pyrrole-containing frameworks via cyclization and cross-coupling reactions.
• Material Science Research: Investigated for the development of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	(E)-Ethyl 2-Oxo-4-(1H-Pyrrol-2-Yl)But-3-Enoate
CAS No.	945736-25-4
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	Ethyl (2E)-2-oxo-4-(1H-pyrrol-2-yl)but-3-enoate; Ethyl (E)-2-oxo-4-(1H-pyrrol-2-yl)-3-butenoate; 2-Butenoic acid, 2-oxo-4-(1H-pyrrol-2-yl)-, ethyl ester, (E)-; 945736-25-4; (E)-Ethyl 2-oxo-4-(1H-pyrrol-2-yl)but-3-enoate
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 2-Oxo-4-(1H-Pyrrol-2-Yl)But-3-Enoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.