Description

6-Chloro-3-Iodo-2-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, where the halogen and fluorine atoms contribute to bioactivity and environmental stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic core.
• Cross-Coupling Reactions: The iodine and chlorine atoms provide orthogonal reactivity for sequential metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig).
• Fluorine Chemistry: Serves as a valuable scaffold for introducing the trifluoromethyl group into more complex molecular architectures.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for client projects.

Basic Information

Product Name	6-Chloro-3-Iodo-2-(Trifluoromethyl)Pyridine
CAS No.	945717-57-7
Molecular Formula	C6H2ClF3IN
Molecular Weight	321.44 g/mol
Synonyms	2-(Trifluoromethyl)-6-chloro-3-iodopyridine; 3-Iodo-6-chloro-2-(trifluoromethyl)pyridine; 6-Chloro-3-iodo-2-trifluoromethylpyridine; Pyridine, 6-chloro-3-iodo-2-(trifluoromethyl)-; 945717-57-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Iodo-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure consistency and reliability for your synthetic workflows. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.