Description

4-Iodo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is a high-value heterocyclic building block featuring a fused pyrrolopyridine core with an iodine substituent. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for constructing diverse compound libraries via cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides with specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular pathways due to its reactive iodine handle.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	4-Iodo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	945600-09-9
Molecular Formula	C7H7IN2
Molecular Weight	246.05 g/mol
Synonyms	4-Iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-iodo-2,3-dihydro-; 4-Iodo-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine; 4-Iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; Pyrrolo[2,3-b]pyridine, 4-iodo-2,3-dihydro-; 945600-09-9; 4-Iodo-1H-pyrrolo[2,3-b]pyridine, 2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 4-Iodo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.