Description

4-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]Oxy]-Benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is a critical building block in modern synthetic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Employed in creating novel active ingredients for crop protection products.
• Material Science Research: Acts as a precursor in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for biological target identification and validation.
• Process Chemistry & Scale-Up: Provides a stable and handleable boronate source for optimizing and scaling synthetic routes from lab to pilot plant.

Basic Information

Product Name	4-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]Oxy]-Benzenamine
CAS No.	945599-51-9
Molecular Formula	C17H21BN2O3
Molecular Weight	312.17 g/mol
Synonyms	4-((3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)aniline; 4-Amino-4'-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yloxy)biphenyl; 2-(4-Aminophenoxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Benzenamine, 4-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]oxy]-; 945599-51-9
EINECS	Contact for details

Quality Control

Our 4-[[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]Oxy]-Benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.