Description

1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid,4-Chloro-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized by R&D teams and production facilities in the pharmaceutical and biotechnology sectors, particularly those focused on developing novel active pharmaceutical ingredients (APIs) and small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research laboratories for structure-activity relationship (SAR) studies and the development of new therapeutic compounds.
• Organic Synthesis: Serves as a versatile precursor for constructing fused heterocyclic systems common in many bioactive molecules.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for use in cGMP-compliant production processes.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents and pesticides.
• Material Science: Investigated for the synthesis of specialized organic electronic materials and ligands for catalysis.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid,4-Chloro-, 1,1-Dimethylethyl Ester
CAS No.	945599-50-8
Molecular Formula	C12H13ClN2O2
Molecular Weight	252.70 g/mol
Synonyms	4-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 4-Chloro-1-(tert-butoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine; 1-Boc-4-chloro-7-azaindole; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; 4-Chloro-7-azaindole-1-carboxylic acid tert-butyl ester; 945599-50-8; tert-Butyl 4-chloro-7-azaindole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid,4-Chloro-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.