Description

5-Bromo-3-Chloropyridine-2-Carbonitrile is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which provides multiple reactive sites for selective functionalization, enabling the construction of complex heterocyclic systems. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to construct novel pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Functional Material Development: Building block for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for target identification and validation.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the bromo and chloro substituents.

Basic Information

Product Name	5-Bromo-3-Chloropyridine-2-Carbonitrile
CAS No.	945557-04-0
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	2-Cyano-5-bromo-3-chloropyridine; 3-Chloro-5-bromopicolinonitrile; 5-Bromo-3-chloro-2-pyridinecarbonitrile; 5-Bromo-3-chloropyridine-2-carbonitrile; 3-Chloro-5-bromo-2-cyanopyridine; 2-Pyridinecarbonitrile, 5-bromo-3-chloro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloropyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency essential for research and scale-up. Certificates of Analysis (COA) with detailed specifications are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.